Most seniors surveyed felt they knew little or nothing about the Medicare drug discount cards. Additionally, just 20 % of these surveyed were aware of the Medicare credit of $600 available for low-income Medicare beneficiaries to help them pay for prescription medications. When they find out about the Medicare credit, more than four out of five believe it will be beneficial to low-income Medicare beneficiaries, including two-thirds who think it’ll be very helpful.For excision of intermediate-thickness and thick melanomas, margins of 2 to 3 3 cm were recommended, with adjustment permissible for anatomical or practical considerations. Sufferers in the observation group underwent delayed lymphadenectomy if nodal metastases developed during observation. Sufferers in the biopsy group underwent instant lymphadenectomy if metastases were detected in sentinel nodes stained with hematoxylin and eosin or immunohistochemically stained for S-100, HMB-45, and melanoma antigen identified by T cells .9,16,17 The presence of immunopositive cells of appropriate cytologic type in nodal parenchyma or in afferent lymphatic vessels was acceptable evidence of a nodal tumor, even if cells were identified by immunohistochemical analysis alone and even if only one particular cell was identified.